Accelerating Biomedical Innovation in Appendiceal Cancer

Welcome to our second in-person conference focusing on Accelerating Biomedical Innovation in Appendiceal Cancer hosted by CANCollaborate with generous support from Christina and Malinda Boothe to be held at MassBio in Cambridge, MA on October 23rd, 2024.

We hope you can join us and are looking forward to hearing about the latest in appendiceal cancer research and treatment. 

Accelerating Biomedical Innovation in Appendiceal Cancer - 2024 Program

8am Registration

8.15am Opening Remarks - Steven Wallman & Jane Wilkinson CANCollaborate

8.30am The Omics of Appendiceal Cancer (Chair - Andreana Holowatyj)

JP Shen, MD Anderson Cancer Center - Network & pathway analysis of multi-‘omics data yields new insights regarding heterogeneity and pathophysiology of appendiceal cancer

Kate Mahon, Chris O'Brien Lifehouse - A snapshot of our appendiceal cancer transcriptomic data

Jorge Barriuso, The Christie - Multiomics in Appendiceal tumours. The CRUK Accelerator Award on Pseudomyxoma Peritonei

Mustafa Raoof, City of Hope - Single cell data on appendiceal cancers

Sara Selitsky, Tempus

Ava Amini, Project Ex Vivo, Microsoft & The Broad Institute - Project Ex Vivo, a collaboration between Microsoft and the Broad Institute

10.00-10.30am Coffee Break

10.30am Bio Markers & Patient Registry and Biosample Sharing (Chair - Kiran Turaga)

Rob Kimmerling, Travera - Cell mass measurements for functional assessment of drug response

Adham Jurdi, Natera - Overview of Signatera data from appendiceal cancers

Xu Han, Wake Forest Health - Cryopreservation of appendiceal cancer cells.

Jim Palma, Target Cancer Foundation - Insight from the TRACK program from an appendiceal view

Susan Horrell, Rare Cancer Research Foundation - RCRF data platform

Jason Foster, University of Nebraska Medical Center - EMR informed patient registry designs and plans using our iCARE2 established registry.

Jay Bader, Yale New Haven Hospital - Creating a national patient-derived registry for running multi-institutional clinical trials in patient with peritoneal surface malignancies

12.00-1.00pm Networking Lunch

1:00pm Novel Therapeutic Approaches (Chair -  David Bartlett)

Jaime Cheah, The Broad Institute - The Drug Repurposing Hub at the Broad Institute

Haroon Choudry, University of Pittsburgh Medical Center - Mucin targeted small molecule therapeutics and nanotherapeutics.

Tatiana Hurtado De Mendoza, University of California, San Diego - Using epigenetics to identify novel therapeutic targets for mucinous appendiceal neoplasms.

JP Shen, MD Anderson Cancer Center - Targeted & immune therapies (and combinations) in appendix cancer: updated clinical and pre-clinical results

2.30pm- 3pm Coffee Break

3:00pm Immuno-oncology and the tumor microenvironment (Chair -  JP Shen)

Patrick Wagner, Allegheny Health Network - The tumor microenvironment of appendiceal cancer

Konstantinos Votanopoulos, Wake Forest Health - Adoptive Immunity Organoid Platform- Generating T cells that recognize and kill appendiceal cancer.

Michael Foote, Memorial Sloan Kettering Cancer Center - Challenges and opportunities in immunology-based treatments for appendix cancer.

Kiran Turaga, Yale School of Medicine - Updates on autoimmunity and appendix cancer

Organizing Committee

Dr. Jamie Barber, CANCollaborate

Dr. JP Shen, MD Anderson Cancer Center

Jane Wilkinson, CANCollaborate